Ultrastructural Orientation of Laminin 5 in the Epidermal Basement Membrane: an Updated Model for Basement Membrane Organization
نویسندگان
چکیده
منابع مشابه
Laminin: the crux of basement membrane assembly
Basement membranes (BMs) are cell-associated sheet-like extracellular matrices covering the basal aspect of all epithelia and endothelia and surrounding muscle, fat, and peripheral nerve cells. BMs are essential for tissue formation in all animals. They provide mechanical stability and barriers between different cell types and are critically involved in cell differentiation, survival, and migra...
متن کاملBasement membrane.
Basement membrane has attracted less attention than the other components of connective tissue. But, like the other extracellular fibres and matrix materials, it can profoundly influence both the structure and function of advanced life forms. Usually taking the shape of thin, structureless cementing material between epithelial and connective tissue, basement membranes are widely distributed thro...
متن کاملBasement Membrane
We report a case of struma ovarii with hyperthyroidism and elevated serum concentrations of type IV collagen and laminin. Circulating levels of type IV collagen and laminin were measured using specific radioimmunoassays (RIAs) for 7S collagen and the P-1 fragment of laminin, and the basement membrane components in the tumor were investigated by immunohistochemical analysis. Strong immunohistoch...
متن کاملExpression of basement membrane laminin in oral squamous cell carcinomas.
UNLABELLED The basement membrane is a dynamic structure that undergoes quantitative and qualitative changes during the progression of squamous cell carcinoma, which is essentially important in tumoral invasion and metastasis. AIM This study is aimed at investigating the behavior of the basement membrane in oral squamous cell carcinomas with different malignancy scores, which were obtained thr...
متن کاملThe Fine Structure of the Basement Membrane in Epidermal Tumors
Epidermal tumors were induced in Swiss female mice by a topical application of 9,10-dimethyl-1,2-benzanthracene solution followed by repeated applications of croton oil solutions. Fourteen benign and malignant tumors were sampled 25 weeks after the treatment had begun, fixed in osmium tetroxide or potassium permanganate, and embedded in Epon. Sections stained with lead hydroxide were examined. ...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2003
ISSN: 0022-1554,1551-5044
DOI: 10.1177/002215540305101007